48.9 M
people affected by sepsis worldwide every year
Rethinking how we treat the most severe infections.
Purotech is a MedTech startup researching new ozone-based solutions with one goal: to give doctors another weapon against sepsis and the infections that antibiotics can no longer stop.
The problem
Sepsis is one of the most serious health emergencies of our time.
Sepsis happens when the body's response to an infection starts damaging its own organs. It can get worse within hours. And as antibiotic-resistant bacteria spread, treating it is becoming harder and harder.
11 M
deaths a year: roughly 1 in 5 deaths worldwide
70,000
sepsis-related deaths in Italy in 2020, up from 19,000 in 2003
1/3
of sepsis deaths in the European Union occur in Italy
What is sepsis?
An extreme reaction of the body to an infection. Instead of defending itself, the body attacks its own tissues and organs. If it isn't recognised and treated quickly, it can lead to septic shock and multiple organ failure.
What is antibiotic resistance?
Some bacteria and other microorganisms have "got used to" medicines and no longer respond to treatment. Infections become harder to treat, spread more easily and are more dangerous.
Sources: Rudd et al., The Lancet (2020); Il Sole 24 Ore (2024); ONsAR – Italian National Observatory on Antimicrobial Resistance; European Sepsis Alliance.
Why ozone
A simple molecule, a powerful ally.
Ozone is a form of oxygen with strong disinfectant properties, already known and used in medicine. Several studies have observed its action against bacteria and viruses.
That's where our research begins.
The project
A new path in the fight against sepsis.
Purotech was founded with a clear idea: to combine the properties of ozone with biomedical engineering to support existing therapies in the care of the most critically ill patients. Every step is taken with the rigour that people's health demands.
Scientific research
We study the effects of ozone together with researchers and clinicians, following a rigorous scientific method.
Innovation
We are working on proprietary technology, born in Italy and designed for the hospital environment.
Safety first
From day one, we follow the European quality and safety standards that apply to medical devices.
Research and collaborations
We don't work alone.
The project grows through a network of collaborations with leading academic, clinical and industrial organisations. Each one brings specific expertise and helps us validate every step.
- Universities and research centres
- Healthcare facilities and clinical laboratories
- Technology and industrial partners
- Quality, regulatory and intellectual property experts
The team
Engineering, experience and vision.
A team that combines decades of experience in healthcare and industry with the drive to build something that matters.
Filippo Calletti
Co-founder & Chairman
Biomedical engineer with over 35 years of experience in the sector. Co-founder and former CEO of Sined S.r.l., a company specialised in information management for healthcare facilities.
Arrigo Monti
Co-founder & CEO
Energy and nuclear engineer, experienced in leading complex industrial programmes. 7 years at GE / Baker Hughes, currently completing an Executive MBA at SDA Bocconi.
Pietro Calletti
Co-founder & Board Member
Business development and B2B sales specialist for startups, educated in the United Kingdom.
Live fully.
Our goal is to help protect and restore people's health by researching next-generation treatments. Because every patient deserves the chance to live fully again.
Contact
Want to know more about Purotech?
Are you a doctor, a research centre, a company or an investor curious about our project? Write to us: we'd be happy to tell you who we are and explore how we could work together.
- Emailinfo@purotech.it
- OfficeBologna, Italy